Video Q & A:

Fibro Medications


Which drugs are specifically approved to treat fibromyalgia ?

Expert:   Betty Keller, MD, FACR, Board Certified Internal Medicine & Rheumatology »

The FDA has approved three drugs to specifically treat fibromyalgia symptoms. See what they are here.

Transcript: There are only three drugs specifically approved to treat fibromyalgia. Their brand names are Lyrica, Cymbalta and Savella. Lyrica is an anti-convulsant initially created to treat epilepsy, and was the first drug approved by the Food and Drug Administration to treat fibromyalgia. Fibromyalgia is thought to be a neurological disorder that is characterized by hyperactive nerve signals and heightened sensitivity to nerve sensations. Lyrica calms down the revved up nerve signals and that decreases the excess pain messages that produce the body-wide discomfort that is so common with fibromyalgia.The antidepressant Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor, or SNRI. It is known to increase levels of those two brain chemicals, called neurotransmitters. These neurotransmitters help control and suppress pain. Researchers think the increased levels of available serotonin and norepinephrine help reduce painful nerve signals associated with fibromyalgia. Savella, is an SNRI, or selective serotonin and norepinephrine reuptake inhibitor. It is similar to SNRIs used to treat depression, but in the U.S. it is ONLY approved to treat fibromyalgia. For people with fibromyalgia it can relieve pain and improve physical function by increasing available levels of serotonin and norepinepherine, two neurotransmitters in the brain that moderate pain. For more answers to your fibromyalgia questions, check out other videos in this series. More »

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